Timothy Ray Brown, the first known person to be cured of HIV, has died of cancer

Timothy Ray Brown, also known as the “Berlin Patient”, was 54 years old.

In 2008, Brown was diagnosed with a HIV infection. The previous year, Brown had undergone bone marrow transplant surgery in Berlin, Germany.

The bone marrow he received came from a donor whose genes contain a rare mutation that makes the donor naturally resistant to HIV. CCR5-Delta32, Which was transferred to Brown.

Brown was HIV-free – but for the past six months he has been living again with leukemia that has entered his spine and brain, according to the International AIDS Society (IAS).

“On behalf of all its members and the Governing Council, the IAS extends its condolences to Timothy’s partner Tim and his family and friends,” said Adiba Kamarulsaman Malaya, president of the International AIDS Society and professor of medicine and infectious diseases at the university, in an IAS statement on Wednesday. .

Worldwide, there are 38 million people He is currently living with HIV / AIDS, according to the United Nations Program on HIV / AIDS.

“We owe it to Timothy and his doctor Zero Hutter to open the door for scientists to explore the possibility of a cure for HIV,” the IAS report said.

The second person to be cured of HIV is still free of the active virus in two years
Brown lived in Berlin from 1993 to 2010, when he worked in a hotel and as a German-English translator, his partner Tim Wrote in a Facebook post. He was diagnosed with HIV in 1995, and was diagnosed with AML in 2007.

Brown wrote, “He did his life’s work to tell his story about his HIV nature and became an ambassador of hope.”

“I’m really happy that we shared a life together, but I was heartbroken that my hero is gone now,” he said. “Tim is truly the sweetest man in the world. Tim’s spirit lives on and the love and support of family and friends will help me through this difficult time.”

Two years ago, Adam Castillejo – formerly known as the “London Patient” – completed HIV antiretroviral therapy, making him the second person to be cured of HIV.

Unlike Brown, Castillejo underwent only one stem cell transplant instead of two and did not have radiotherapy for his entire body as part of his treatment.

CNN’s Gina Yu and Amy Udyot contributed to the report.

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